"inhibition assay study of purified glutathione s-transferase from fasciola hepatica and sheep liver tissue by hexachlorophene"

Inhibition Assay Study of Purified Glutathione S-transferase from Fasciola Hepatica and Sheep Liver Tissue by Hexachlorophene

Glutathione S-transferases (GSTs) are widespread in Fasciola. hepatica parasite and sheep liver tissue. Study of GSTs inhibition assays in F. hepatica and sheep liver tissue are a priority of chemotherapeutic targets in parasitic liver diseases including human fascioliasis in Iran. In this research, the whole extract of F. hepatica and sheep liver tissues were purified and eluted for sodium dod...

characterization of purified glutathione s-transferase (gsts) from fasciola hepatica and liver tissue by two-dimensional electrophoresis (2-de)

two-dimensional electrophoresis (2-d electrophoresis) is a powerful and extensively used method for analysis of complex protein mixtures extracted from cells, tissue, or other biological samples such as helminth parasites including, f. hepatica. each spot on the resulting two-dimensional collection corresponds to a single protein species in the sample. this study was carried out to detect of gs...

study on glutathione s-transferase (gst) inhibition assay by triclabendazole. і: protoscoleces (hydatid cyst; echinococcus granulosus) and sheep liver tissue

hydatid disease is a term used to refer infection with the methacestode of echinococcus granulosus parasite in humans, and echinococcusis is restricted to infection with the adult stage in carnivores.glutathione s-transferase (gst) represents the major class of detoxification enzymes from helminth parasites such as echinococcus protoscoleces (psc) and it is candidate for chemotherapeutic and va...

Cellular Immune Responses in Sheep against Glutathione S-transferase of Fasciola gigantica

"comparative glutathione s-transferases (gsts) inhibition assay in the whole extract of fasciola hepatica and sheep liver tissue by hexachlorophene"

recent research highlights the importance of gsts in the establishment of chronic helminth infections. gsts have the potential to protect the parasite against the host immune response. in this present study, gst enzyme assay has been investigated on whole extract of f. hepatica and sheep liver tissue. to the 1-ml plastic cuvette, added 200 mm potassium phosphate buffer. then added 50 mm gsh red...

The Sigma Class Glutathione Transferase from the Liver Fluke Fasciola hepatica

BACKGROUND Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no commercial vaccines, and only one drug with significant efficacy against adult worms and juveniles. A liver fluke vaccine is deemed essential as short-lived chemotherapy, which ...